If the player does not rescue Mary but escapes with the science logs, Hawking is still attacked by Annar. By firing their weapon at the right time, the player can shoot and kill Annar on board the rescue craft, Hawking is reunited with Mary. If the player rescues Mary and escapes the ship with the science logs, Hawking is attacked on board the escape shuttle by Annar, who does not want knowledge of the experiments to leak out. The ending of the game varies depending on different actions taken by the player:

Using the Firestart scientists' notes on the genetic flaws in their original organisms, he must improvise a way to kill the creature using the resources available to him on board the ship. The supercreature then seeks out Hawking, who discovers that it is completely invulnerable to all of his weaponry. The creatures spawn a giant, white version of themselves, which begins attacking them. Also in cryosleep is Mary, another Firestart scientist who survived the massacre because she was placed in suspended animation after suffering a minor injury. Arno, survived by placing himself in cryosleep upon Hawking's arrival on the Prometheus, he awakens. SIA Agent Annar Kensan, who was working in secret with Dr. Unable to contain the monsters, the crew of the Prometheus was slaughtered. The plan backfired, as Arno's creations proved to be mindlessly hostile and capable of asexual reproduction. Arno, secretly altered the DNA of the mining creatures in an attempt to create a race of super soldiers. Hawking further learns that one of the scientists on the project, Dr. Retrieving the ship's science logs, Hawking discovers that Project Firestart was a genetic engineering program that sought to create a mining species resistant to extreme cold and low oxygen levels by combining the DNA of oxen with a new species of fungi discovered in asteroids around Titan. On board the Prometheus, Hawking discovers the entire crew brutally murdered and the ship infested with large, hostile creatures. Should Hawking fail in his mission, the USS will remotely activate the Prometheus' self destruct sequence on the assumption that Hawking himself has been killed. Hawking is further instructed to retrieve all of the scientific data on board the Prometheus and then to destroy the ship, based on the USS' belief that Project Firestart has been compromised and could potentially pose a threat to Earth. Hawking's mission is to make contact with the members of Project Firestart, an initiative of the System Science Foundation, who have recently dropped out of communication with their superiors on Earth. In 2061, agent Jon Hawking of the United System States is sent to the research ship Prometheus, in orbit around Titan. The game has been cited by various gaming journalists and writers as one of, if not the first, survival horror game, pioneering many conventions of the genre including limited ammunition, an emphasis on escaping enemies and puzzle solving over combat, solving a central mystery, and multiple endings. Taking place in the 21st century, the game follows a government agent dispatched to a research station in orbit around Saturn's moon, Titan, to learn why the scientists there abruptly cut off communication with Earth. It was designed by Jeff Tunnell and Damon Slye and published by Electronic Arts in 1989. Project Firestart is a cinematic survival horror game for the Commodore 64 computer system.

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